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Guidalberto Manfioletti Selected Research

HMGA Proteins

10/2020Targeting the intrinsically disordered architectural High Mobility Group A (HMGA) oncoproteins in breast cancer: learning from the past to design future strategies.
1/2020High Mobility Group A (HMGA): Chromatin Nodes Controlled by a Knotty miRNA Network.
1/2019HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion.
4/2018High Mobility Group A (HMGA) proteins: Molecular instigators of breast cancer onset and progression.
7/2011Conformational role for the C-terminal tail of the intrinsically disordered high mobility group A (HMGA) chromatin factors.
5/2011HMGA Interactome: new insights from phage display technology.
1/2007The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function.
11/2005HMGA proteins in malignant peripheral nerve sheath tumor and synovial sarcoma: preferential expression of HMGA2 in malignant peripheral nerve sheath tumor.
4/2005Discovering high mobility group A molecular partners in tumour cells.
2/2005Differential HMGA expression and post-translational modifications in prostatic tumor cells.
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Guidalberto Manfioletti Research Topics

Disease

30Neoplasms (Cancer)
01/2021 - 03/2002
11Breast Neoplasms (Breast Cancer)
05/2022 - 07/2006
4Triple Negative Breast Neoplasms
05/2022 - 08/2019
3Neoplasm Metastasis (Metastasis)
05/2022 - 07/2006
3Carcinoma (Carcinomatosis)
07/2006 - 03/2002
2Type 2 Diabetes Mellitus (MODY)
01/2012 - 07/2005
2Retinoblastoma (Glioblastoma, Retinal)
03/2009 - 05/2003
2Thyroid Neoplasms (Thyroid Cancer)
03/2006 - 03/2002
2Carcinogenesis
04/2003 - 07/2002
1Glioblastoma (Glioblastoma Multiforme)
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2013
1Embryonal Rhabdomyosarcoma
12/2007
1Ganglion Cysts (Ganglion)
12/2007
1Ganglioneuroma
12/2007
1Synovial Sarcoma (Synovioma)
11/2005
1Neurofibrosarcoma (MPNST)
11/2005
1Insulin Resistance
07/2005
1Prostatic Neoplasms (Prostate Cancer)
02/2005
1Dermatofibrosarcoma
08/2004
1Benign Fibrous Histiocytoma (Dermatofibroma)
08/2004
1Ovarian Epithelial Carcinoma
07/2003
1Ovarian Neoplasms (Ovarian Cancer)
07/2003
1Adenocarcinoma
07/2003
1Hamartoma
07/2002
1Leiomyoma (Uterine Fibroids)
07/2002
1Tuberous Sclerosis (Bourneville's Disease)
07/2002
1Lipoma (Lipomata)
07/2002
1Adenoma (Adenomas)
03/2002

Drug/Important Bio-Agent (IBA)

21Proteins (Proteins, Gene)FDA Link
05/2022 - 03/2002
13HMGA ProteinsIBA
10/2020 - 07/2002
8ChromatinIBA
05/2022 - 09/2004
6Transcription Factors (Transcription Factor)IBA
01/2021 - 05/2003
4DNA (Deoxyribonucleic Acid)IBA
01/2016 - 07/2002
4HMGA2 ProteinIBA
01/2013 - 07/2002
3Biological ProductsIBA
04/2018 - 07/2002
2CyclinsIBA
01/2021 - 08/2015
2Histones (Histone)IBA
08/2019 - 06/2019
2Insulin ReceptorIBA
01/2012 - 07/2005
1StathminIBA
05/2022
1Pharmaceutical PreparationsIBA
01/2022
1Oncogene Proteins (Oncogene Protein)IBA
10/2020
1MicroRNAs (MicroRNA)IBA
01/2020
1CREB-Binding ProteinIBA
08/2019
1polypeptide 3 90kDa ribosomal protein S6 kinaseIBA
08/2019
1Hormones (Hormone)IBA
01/2019
1PlasminogenIBA
01/2017
1Plasminogen Activators (Plasminogen Activator)IBA
01/2017
1Biomarkers (Surrogate Marker)IBA
01/2013
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
07/2010
1ParaffinIBA
03/2009
1Genetic Markers (Genetic Marker)IBA
12/2007
1Transforming Growth Factor beta (TGF-beta)IBA
07/2006
1Small Interfering RNA (siRNA)IBA
03/2006
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2006
1Insulin (Novolin)FDA Link
07/2005
1PhosphoproteinsIBA
09/2004
1Factor XIIIaIBA
08/2004
1Staphylococcal Protein A (Protein A)IBA
05/2003
1High Mobility Group ProteinsIBA
04/2003
1HMGA1a ProteinIBA
04/2003
1Nuclear Proteins (Protein, Nuclear)IBA
04/2003
1Messenger RNA (mRNA)IBA
03/2002

Therapy/Procedure

2Therapeutics
08/2019 - 01/2019
2Drug Therapy (Chemotherapy)
12/2007 - 09/2004